منابع مشابه
Rhinostomies: an open and shut case?
AIMS To analyse bone fragments from rhinostomies of patients undergoing revisional dacryocystorhinostomy, looking for evidence of new bone formation. METHODS 14 consecutive patients undergoing secondary lacrimal surgery were included in this study. In each case the existing rhinostomy was enlarged with bone punches, care being taken to use the punches with the jaws cutting perpendicularly to ...
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Molecular events in the clamp-loading reaction pathway of DNA replication are revealed by new crystal structures of bacteriophage T4 clamp loader-clamp-DNA complexes that capture two distinct conformations with the clamp open and closed.
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Thirty-seven years ago, it was suggested that abscesses could be treated with primary closure rather than by conventional incision and drainage, and that subsequent healing was superior. The result of a survey into the practice and teaching of abscess management in accident and emergency departments shows that, despite apparent satisfaction with the technique, it has not gained widespread accep...
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Recent crystallographic studies have provided significant new insight into how receptor tyrosine kinases from the EGF receptor or ErbB family are regulated by their growth factor ligands. EGF receptor dimerization is mediated by a unique dimerization arm, which becomes exposed only after a dramatic domain rearrangement is promoted by growth factor binding. ErbB2, a family member that has no lig...
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P otassium channels are highly complex molecular systems that modulate the cell potential in response to extracellular or intracellular signals. In multicellular organisms, K currents are essential to electrical signaling, governing central nervous system, cardiac, renal, and a host of other organ functions. Publication of the first K channel structure in 1998 (1) represented a landmark in our ...
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ژورنال
عنوان ژورنال: Trends in Biochemical Sciences
سال: 2007
ISSN: 0968-0004
DOI: 10.1016/j.tibs.2006.12.003